Cytomegalovirus (CMV) is a herpes viral genus of the Herpesviruses group: in humans it is commonly known as HCMV or Human herpesvirus 5 (HHV-5). HCMV infection is widespread in developing countries and in communities with lower socioeconomic status and represents the most significant viral cause of birth defects in industrialized countries. CMV-speciﬁc immunoglobulin M (IgM) is a sensitive and speciﬁc indicator of active or recent CMV infection, while it is very often produced during viral reactivation in immunocompromised individuals. pp65 (UL83) is a phosphoprotein located in the nucleolar matrix of lytically infected fibroblasts. This tegument protein pp65 was found to be most prominent at early times after HCMV infection.
|GENBANK ACC (gene)||NC_006273.2|
|GENBANK ACC (protein)||AAR31635.1|
|DESCRIPTION||The recombinant antigen pp65 from CMV is a phosphoprotein located in the nucleolar matrix of lytically infected fibroblasts. It has been prepared as a recombinant antigen containing the major exon of UL83 gene|
|PURITY||> 95% in a 15 % SDS-PAGE|
|SHIPPING AND STORAGE CONDITIONS||Proteins may be shipped on dry ice or ice pack. Upon arrival they should be stored at -20ºC to -80ºC. Avoid multiple freeze/thaw cycles|
|ESTABILITY||The protein will remain stable for five years if stored frozen|
|ESPECIFICITY||Immunoreactive with sera of CMV-infected individuals|
|APPLICATIONS||Antigen for using in ELISA, immunochromatography, dot blot and western blot assays. FOR RESEARCH USE ONLY|
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