Recombinant antigen gp40 for FIV

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gp40 -is a transmembrane glycoprotein responsible for viral membrane fusion with the host cell membrane. The gp40 subunit contains different functional regions in its ectodomain: the fusion peptide (FP), heptad repeat 1 (HR1), HR2, and the transmembrane region. This protein is very similar to gp41 from HIV. The sequence of gp40 contains four functional regions, as follows: the N-terminal fusion peptide (which is thought to insert into the host cell membrane) is followed by an ectodomain, a transmembrane region and a cytoplasmic domain.

For diagnosis of the disease in cats.

View more information about Acquired feline immunodeficiency syndrome.

REFERENCES

RAG0066

WB, DB, Indirect ELISA, positive control in direct ELISA

GENE

env

DESCRIPTION

Transmembrane subunit of the 150 kDa envelope glycoprotein

PURITY

>95% in a SDS-PAGE

SHIPPING AND STORAGE CONDITIONS

Proteins will be shipped with dry ice or lyophilized. Upon arrival (if liquid), or after reconstitution (if lyophilized), they should be stored at -20ºC to -80ºC. Avoid multiple freeze/thaw cycles

STABILITY

The protein will remain stable for four years if stored frozen

SPECIFICITY

Not tested. According to the literature, the protein is immunoreactive against seropositive individuals to Acquired feline immunodeficiency syndrome

IVD

FIV serodiagnosis

PROMOTIONAL MATERIAL

Catalogue

FOR RESEARCH AND COMERCIAL USE IVD ONLY (*)

(*) Our antigens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. For more information about the general features of our antigens, you can visit here.

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