High quality raw material for IVD manufacturing industry

Recombinant antigen p29 (GRA7) for Toxoplasma gondii

RekomVet
Toxoplasma gondii

Toxoplasmosis is a disease caused by the parasite Toxoplasma gondii which is one of the most common parasitic diseases and infects nearly all warm-blooded animals, including pets and humans. Although cats are a necessary part of the life cycle of T. gondii, the parasite rarely causes clinical disease in them. While T. gondii seldomly causes significant symptoms in healthy adults either, the Center for Disease Control and Prevention (CDC) has identified toxoplasmosis as one of five neglected parasitic infections of people due to its high prevalence. Therefore, diagnosis of toxoplasmosis is useful for human and animal health to control its spread. Several techniques are employed for the diagnosis in feline and canine population. One example is the serological detection of T. gondi, which has been described for pigs, goats, dogs, and cats.

p29 (GRA7) is a protein present in the dense granules of Toxoplasma gondii, with a size of 29 kDa. It is a protein secreted by bradyzoites, which has a high response to IgG in human sera infected with T. gondii. However, it has been described in the bibliography, which has been determined for this protein by means of ELISA tests, a high sensitivity against human sera with antibodies of the IgM type, being therefore also useful for the determination of acute disease.

For diagnosis of the disease in birds and mammals, mainly cats.

View more information about Toxoplasmosis.

REFERENCES
COA RAG0083 new WB, DB, Indirect ELISA, positive control in direct ELISA, CLIA, lateral-flow
GENE
GRA7
DESCRIPTION
Dense granule antigen
PURITY
>95% in a SDS-PAGE
SHIPPING AND STORAGE CONDITIONS
Proteins will be shipped with dry ice or lyophilized. Upon arrival (if liquid), or after reconstitution (if lyophilized), they should be stored at -20ºC to -80ºC. Avoid multiple freeze/thaw cycles
STABILITY
The protein will remain stable for four years if stored frozen
SPECIFICITY
Not tested
IVD
Serodiagnosis of human and animal toxoplasmosis

Also avaliable for detection of Toxoplasmosis in humans

FOR RESEARCH AND COMERCIAL USE IVD ONLY (*)

(*) Our antigens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. For more information about the general features of our antigens, you can visit here.

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