Toxoplasmosis is a disease caused by the parasite Toxoplasma gondii which is one of the most common parasitic diseases and infects nearly all warm-blooded animals, including pets and humans. Although cats are a necessary part of the life cycle of T. gondii, the parasite rarely causes clinical disease in them. While T. gondii seldomly causes significant symptoms in healthy adults either, the Center for Disease Control and Prevention (CDC) has identified toxoplasmosis as one of five neglected parasitic infections of people due to its high prevalence. Therefore, diagnosis of toxoplasmosis is useful for human and animal health to control its spread. Several techniques are employed for the diagnosis in feline and canine population. One example is the serological detection of T. gondi, which has been described for pigs, goats, dogs, and cats.
p29 (GRA7) is a protein present in the dense granules of Toxoplasma gondii, with a size of 29 kDa. It is a protein secreted by bradyzoites, which has a high response to IgG in human sera infected with T. gondii. However, it has been described in the bibliography, which has been determined for this protein by means of ELISA tests, a high sensitivity against human sera with antibodies of the IgM type, being therefore also useful for the determination of acute disease.
For diagnosis of the disease in birds and mammals, mainly cats.
FOR RESEARCH AND COMERCIAL USE IVD ONLY (*)
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