Recombinant antigen K39 for
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K39 is a repetitive immunodominant epitope in a kinesin-related protein that is highly conserved among viscerotropic Leishmania species. It has been described that a rK39 ELISA is sensitive and specific for serodiagnosis of human and canine VL.
View more information about Leishmaniosis.
WB, DB, Indirect ELISA, positive control in direct ELISA, CLIA, lateral-flow
WB, DB, Capture ELISA, Double Antigen Sandwich (DAS), nanoparticles binding, plate orientation
Parasite kinesin-related antigen
>98% in a SDS-PAGE
SHIPPING AND STORAGE CONDITIONS
Proteins will be shipped with dry ice or lyophilized. Upon arrival (if liquid), or after reconstitution (if lyophilized), they should be stored at -20ºC to -80ºC. Avoid multiple freeze/thaw cycles
The protein will remain stable for four years if stored frozen
The protein is immunoreactive against seropositive individuals to Leishmaniosis
Serodiagnosis of human and animal leishmaniosis
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LIST OF CITATIONS
Abass E., Bollig N., Reinhard K., et al. rKLO8, a novel Leishmania donovani - derived recombinant immunodominant protein for sensitive detection of visceral leishmaniasis in Sudan (2013). PLoS neglected tropical diseases, vol. 7,7 e2322.
Mollett G., Bremer Hinckel B.C., Bhattacharyya T., et al. Detection of Immunoglobulin G1 Against rK39 Improves Monitoring of Treatment Outcomes in Visceral Leishmaniasis (2019). Clin Infect Dis, 69(7):1130-1135.
Also avaliable for detection of Leishmaniosis in animals
FOR RESEARCH AND COMERCIAL USE IVD ONLY (*)
(*) Our antigens are provided for research and commercial use
in vitro: not for human in vivo or therapeutic use. For more information about the general features of our antigens, you can visit here.
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