Recombinant early antigen p54 for Epstein-barr virus

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D-EA p54 (p47/54) is considered as diffused (EA-D) early antigen. Regarding the EA-D, it is located in nucleus and cytoplasm and it has been described the highly presence of the diffuse early antigen of EBV in lymphomas and lymphoproliferative disorders. The D-EA p54 is an antigen codified by the BMRF1 gene, which is a DNA polymerase processivity factor. At the time of infection with Epstein-Barr virus, antibodies to EA are found and usually last for four to six months only. The absence of antibody to EA when other EBV antibodies are present strongly suggests that first time infection with EBV occurred in the past.

View more information about Epstein-Barr virus infection.

REFERENCES

RAG0035 WB, DB, Indirect ELISA, positive control in direct ELISA

GENE

BMRF1 (UL42)

DESCRIPTION

Early antigen

PURITY

>95% in a SDS-PAGE

SHIPPING AND STORAGE CONDITIONS

Proteins will be shipped with dry ice or lyophilized. Upon arrival (if liquid), or after reconstitution (if lyophilized), they should be stored at -20ºC to -80ºC. Avoid multiple freeze/thaw cycles

STABILITY

The protein will remain stable for four years if stored frozen

SPECIFICITY

The protein is immunoreactive against seropositive individuals to Epstein-Barr virus infection

IVD

Serodiagnosis of infectious mononucleosis associated to EBV and primary acute infections in immunocompromised individuals

Biotinylated antigens

PROMOTIONAL MATERIAL

Catalogue
Rekom EBV high quality raw material