High quality raw material for IVD manufacturing industry

Recombinant antigen p35 (GRA8) for Toxoplasma gondii

RekomVet
Toxoplasma gondii

Toxoplasmosis is a disease caused by the parasite Toxoplasma gondii which is one of the most common parasitic diseases and infects nearly all warm-blooded animals, including pets and humans. Although cats are a necessary part of the life cycle of T. gondii, the parasite rarely causes clinical disease in them. While T. gondii seldomly causes significant symptoms in healthy adults either, the Center for Disease Control and Prevention (CDC) has identified toxoplasmosis as one of five neglected parasitic infections of people due to its high prevalence. Therefore, diagnosis of toxoplasmosis is useful for human and animal health to control its spread. Several techniques are employed for the diagnosis in feline and canine population. One example is the serological detection of T. gondi, which has been described for pigs, goats, dogs, and cats.

p35 (GRA8), a 35 kDa protein, has been described as a marker of acute infection able to differentiate acute from chronic infection. There are three secretory organs present in Toxoplasma gondii cytoplasm, as the dense granules. Dense granule antigens (GRA), secreted in abundance are highly immunodominant and induce strong antibody response.

For diagnosis of the disease in birds and mammals, mainly cats.

View more information about Toxoplasmosis.

REFERENCES
RAG0084 WB, DB, Indirect ELISA, positive control in direct ELISA, CLIA, lateral-flow
GENE
GRA8
DESCRIPTION
Dense granule antigen
PURITY
>95% in a SDS-PAGE
SHIPPING AND STORAGE CONDITIONS
Proteins will be shipped with dry ice or lyophilized. Upon arrival (if liquid), or after reconstitution (if lyophilized), they should be stored at -20ºC to -80ºC. Avoid multiple freeze/thaw cycles
STABILITY
The protein will remain stable for four years if stored frozen
SPECIFICITY
The protein is immunoreactive against seropositive individuals to Toxoplasmosis
IVD
Serodiagnosis of human and animal toxoplasmosis
PROMOTIONAL MATERIAL
RELATED PRODUCTS

FOR RESEARCH ANDCOMERCIAL USE IVD ONLY (*)

(*) Our bio-markers are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. For more information about the general features of our bio-markers, you can visit here.

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