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CHIMERAS: MULTI-EPITOPE ANTIGENS

9/9/2019

Chimera

Figure 1. Chimeras

At Rekom Biotech, we have specialized in the design and production of next-generation antigens: chimeras or antigens composed of multiple epitopes, which have improved their antigenic properties, such as sensitivity and specificity. Furthermore, one main advantage of the multi-epitope chimeric antigens is avoiding the use of protein mixtures in your assay. The limited number of binding sites and the different affinities of proteins for these sites could result in reproducibility issues.

EPITOPE ANALYSIS

Epitope analysis

SEQUENCE ANALYSIS

Sequence analysis

3D STUDIES

3D Studies

Rekom Biotech chimeras

DISEASE/ALLERGY NAME REFERENCE DESCRIPTION
ChimLyme
(humans)
(animals)
RAG0027 (B. burgdorferi, chimera) Recombinant chimeric antigen for Borrelia burgdorferi
ChimChagas1
(humans)
(animals)
RAG0093 (chimera) Recombinant chimeric antigen for Chagas detection
ChimChagas2
(humans)
(animals)
RAG0094 (chimera) Recombinant chimeric antigen for Chagas detection
ChimChagas3
(humans)
(animals)
RAG0096 (chimera)
RAG0096BIOT (biotinylated)
Recombinant chimeric antigen for Chagas detection
ChimToxo1
(humans)
(animals)
RAG0058 (chimera) Recombinant chimeric antigen ChimToxo1 for toxoplasmosis detection (SAG1 and GRA8)
CFP10:ESAT6
(humans)
(animals)
RAG0060 (chimera) Recombinant chimeric antigen formed by the proteins CFP10 and ESAT6

Written by Ana Camacho.