Ehrlichiosis

Ehrlichiosis is a disease caused by bacteria of the genus Ehrlichia, which attack white blood cells. This disease can be contracted by animals and humans, being Ehrlichia canis the one that most commonly affects the canine species. Ehrlichiosis is transmitted through tick bites, not through direct contact with infected animals. On rare occasions, it can be transmitted by blood transfusion. The most common symptoms depend on the phase of the disease, being mild to moderate, and can even cause death. The most common are fever, weight loss, lethargy, swollen joints, brain or glands, bleeding and seizures. The treatment consists of giving antibiotics, doxycycline. If treated early in the disease, it is almost completely curable. As prevention it is recommended to avoid tick bites, checking the dog before and after each walk, avoiding wet areas and thickets, combing the animal and using antiparasitic products. Since the symptoms are very similar to other diseases and the infection can remain active for a few weeks, or become chronic and cause long-term problems, early diagnosis is very important, and it can be done through peripheral blood smears with a microscope, a serological test or PCR.

Canine ehrlichiosis is present throughout the world, particularly in tropical and subtropical areas, and is more prevalent in the warmer months, as ticks are more active.

Animal infectious disease (mainly to humanos)

At Rekom Biotech, we desing and manufacture IVD reagents for diagnosis of Ehrlichiosis. Do not hesitate to contact us!

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BACT TO LIST OF INFECTIOUS DISEASES

Recombinant proteins

DISEASE/MICROORGANISM NAME REFERENCES DESCRIPTION DETAILS

Ehrlichiosis / Ehrlichia canis

gp19
RAG0025 New
Glycoprotein gp19 of Ehrlichia canis

Pipeline

Recombinant proteins

Design

Protein design from scratch, always trying to improve its antigenic capacity.

Verification

Search for the best DNA construction according to the design phase.

Expression system

Selection of the best expression system for the protein.

USP/DSP process tuning

Process adjustments to achieve an optimal seed, and the process to isolate our protein from the obtained seed.

Validation

Validation and full quality control.

p28/p30 for Ehrlichiosis caused by Ehrlichia canis (animal)
Design