Multi-epitope recombinant chimeric proteins

At Rekom Biotech, we use computational methods to access structural models of antigenic molecules. This allows us to select specific antigenic domains from different proteins. We then combine them using long, short, flexible, or rigid linkers to enable simultaneous interaction of every epitope with its corresponding paratope. By avoiding steric hindrance, by using the appropriate linker, two or three different antibodies can interact with the multi-epitope molecule, increasing sensitivity. Our chimeric multi-epitope proteins are also highly specific as we select domains that differentiate this microorganism from its counterparts.

In addition, using multi-epitope chimeric proteins has another significant benefit of eliminating the need for protein mixtures in assays. When using protein mixtures, the limited number of binding sites and varying affinities of proteins for these sites may lead to issues with reproducibility.

Take a look at our multi-epitope recombinant chimeric proteins and do not hesitate to contact us if you need anything.

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DISEASE/ALLERGY NAME CAT NUMBER DESCRIPTION DETAILS

Babesiosis (or piroplasmosis)

ChimBc
RAG0040 (B. canis, chimera)
Multi-epitope recombinant chimeric antigen for Babesia canis
ChimBg
RAG0045 (B. gibsoni, chimera) New
Multi-epitope recombinant chimeric antigen for Babesia gibsoni

Chagas / Trypanosoma cruzi

ChimChagas1
RAG0093 (chimera) Top product (Satisfaction guarantee)
Multi-epitope recombinant chimeric antigen for Chagas
ChimChagas2
RAG0094 (chimera) Top product (Satisfaction guarantee)
Recombinant chimeric antigen for Chagas detection
ChimChagas3
RAG0096 (chimera) Top product (Satisfaction guarantee)
Multi-epitope recombinant chimeric antigen for Chagas

Cytomegalovirus infection (CMV)

ChimCMV1
RAG0109 (chimera) Top product (Satisfaction guarantee)
RAG0109BIOT (biotinylated, chimera)
Multi-epitope recombinant chimeric antigen for CMV
ChimCMV2
RAG0110 (chimera)
RAG0110BIOT (biotinylated, chimera)
Multi-epitope recombinant chimeric antigen for CMV
ChimCMV3
RAG0018 (chimera) New
Multi-epitope recombinant chimeric antigen for CMV

Dirofilariasis / Dirofilaria immitis

ChimDiT33
RAG0014 (chimera)
Multi-epitope recombinant chimeric antigen for Dirofilaria immitis

Epstein-Barr virus infection (EBV)

ChimEBV-EA
RAG0082 (chimera) New
Multi-epitope recombinant chimeric early antigen for Epstein-Barr Virus (EBV)
ChimEBV-VCA
RAG0081 (chimera) New
Multi-epitope recombinant chimeric viral capsid antigen for Epstein-Barr Virus (EBV)

Lyme borreliosis (or Lyme disease)

VlsE
RAG0022 (B. garinii, chimera)
RAG0027 (B. burgdorferi, chimera) Top product (Satisfaction guarantee)
Major variable Surface antigen

Syphilis / Treponema pallidum

ChimSyphilis1
RAG0046 (chimera) Top product (Satisfaction guarantee)
RAG0046BIOT (biotinylated, chimera)
Multi-epitope recombinant chimeric antigen for Treponema pallidum
ChimSyphilis2
RAG0064 (chimera)
RAG0064BIOT (biotinylated, chimera)
Multi-epitope recombinant chimeric antigen for Treponema pallidum

Toxoplasmosis / Toxoplasma gondii

ChimToxo1
RAG0058 (chimera)
Multi-epitope recombinant chimeric antigen for Toxoplasmosis (SAG1 and GRA8)

Tuberculosis (TB) / Mycobacterium tuberculosis (Koch's bacillus)

CFP10:ESAT6
RAG0060 (chimera)
Multi-epitope recombinant chimeric antigen for Tuberculosis (CFP10 and ESAT6)

Aligment

Chimera