Recombinant antigen p44 for Anaplasma phagocytophilum

Anaplasma phagocytophilum

p44 is the immunodominant, most abundant outer membrane protein of Anaplasma phagocytophilum, an obligate intracellular bacteria that causes a tick-borne zoonosis termed human granulocytic anaplasmosis (HGA), the most common tick transmitted disease after borreliosis. The immunodominant polymorphic 44-kDa major surface proteins of A. phagocytophilum, is a member of the p44/msp2 multigene family and are encoded by more than 80 p44 paralogs dispersed throughout the genome. The 44-kDa-protein-specific antibodies play a role in immunity against infection. This immunogenic antigen is therefore important in pathogenesis and laboratory diagnosis.

Disease caused mainly to dogs, cats, horses, sheep and cattle.

More information about Anaplasmosis caused by Anaplasma phagocytophilum.

or
Name
p44
Description
Outer membrane antigen for Anaplasma phagocytophilum
Gene
p44
Purity
> 95% by observation on SDS-PAGE electrophoresis
References
SKU Source Applications In-house validation Details
RAG0026 New E. coli WB, DB, IE, DE, CLIA, LF - Example of a certificate of analysis Material Safety Data Sheet
WB: Western Blot | DB: Dot Blot | IE: Indirect ELISA | DE: positive control in Direct ELISA | CLIA: Chemiluminescent immunoassay | LF: Lateral-Flow | CE: Capture ELISA | DAS: Double Antigen Sandwich ELISA | NP: Nanoparticles binding | PO: Plate orientation | COA: Certificate of analysis | SDS: Material Safety Data Sheet
Formats
Liquid solution or dry powder (lyophilised) in vials of 0.1 mg, 1 mg and bulk

Also avaliable for diagnosis of Anaplasmosis caused by Anaplasma phagocytophilum in humans

For research and comercial use IVD only (*)

(*) Our IVD reagents are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. You can get more information about the general features and about the shipping, storage, defrost, manipulation and stability of all of our reagents. In addition, we follow a rigorous quality control for each lot.

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