Recombinant antigen S1 (RBD) COVID-19 for SARS-CoV-2

SARS-CoV-2

Coronaviruses are enveloped viruses possessing large, trimeric spike glycoproteins (S) required for the recognition of host receptors for many coronaviruses as well as the fusion of viral and host cell membranes for viral entry into cells. During viral egress from infected host cells, some coronavirus S proteins are cleaved into S1 and S2 subunits. The S1 subunit is responsible for host-receptor binding while the S2 subunit contains the membrane-fusion machinery. Thus, S1 subunit contains the receptor-binding domain (RBD), located in the C-terminal region. This domain is used as a biomarker for COVID diagnostic.

Recombinant antigen for the diagnosis of Coronavirus (COVID-19) caused by SARS-CoV-2, a human infectious disease.

or
Name
S1 (RBD) COVID-19
Description
S1 Receptor Binding Domain (RBD)
Gene
S
Purity
> 95% by observation on SDS-PAGE electrophoresis
Cat number
SKU Source Applications In-house validation Details
RAG0074 P. pastoris WB, DB, IE, DE, CLIA, LF Immunoassay blocker ELISA Example of a certificate of analysis Material Safety Data Sheet
WB: Western Blot | DB: Dot Blot | IE: Indirect ELISA | DE: positive control in Direct ELISA | CLIA: Chemiluminescent immunoassay | LF: Lateral-Flow | CE: Capture ELISA | DAS: Double Antigen Sandwich ELISA | NP: Nanoparticles binding | PO: Plate orientation | COA: Certificate of analysis | SDS: Material Safety Data Sheet
Immunoassay blocker Due to the nonspecific interaction with anti-CCDs present in normal human or animal sera, we strongly recommend using our blocker SOR0001 on the analyzed sera in any immunoassay.
Formats
Liquid solution or dry powder (lyophilised) in vials of 0.1 mg*, 1 mg and bulk
* under availability, for liquid format
Related proteins
NP (CTD) NP (CTD) COVID-19

For research and comercial use IVD only (*)

(*) Our IVD reagents are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. You can get more information about the general features and about the shipping, storage, defrost, manipulation and stability of all of our reagents. In addition, we follow a rigorous quality control for each lot.

Bact to list of Recombinant antigens for infectious diseases

How to reconsitute lyophizated vials

How to use the inmunoassay blocker for anti-cross-reactive carbohydrate determinants (CCD) antibodies