Recombinant antigen S1 (RBD) COVID-19 for SARS-CoV-2

SARS-CoV-2

Coronaviruses are enveloped viruses possessing large, trimeric spike glycoproteins (S) required for the recognition of host receptors for many coronaviruses as well as the fusion of viral and host cell membranes for viral entry into cells. During viral egress from infected host cells, some coronavirus S proteins are cleaved into S1 and S2 subunits. The S1 subunit is responsible for host-receptor binding while the S2 subunit contains the membrane-fusion machinery. Thus, S1 subunit contains the receptor-binding domain (RBD), located in the C-terminal region. This domain is used as a biomarker for COVID diagnostic.

More information about Coronavirus (COVID-19) caused by SARS-CoV-2.

or
Name
S1 (RBD) COVID-19
Description
SARS-CoV-2 S1 Receptor Binding Domain (RBD)
Gene
S
Purity
> 95% by observation on SDS-PAGE electrophoresis
References
SKU Source Applications In-house validation Details
RAG0074 New P. pastoris WB, DB, IE, DE, CLIA, LF Sorbent ELISA Example of a certificate of analysis Material Safety Data Sheet
WB: Western Blot | DB: Dot Blot | IE: Indirect ELISA | DE: positive control in Direct ELISA | CLIA: Chemiluminescent immunoassay | LF: Lateral-Flow | CE: Capture ELISA | DAS: Double Antigen Sandwich ELISA | NP: Nanoparticles binding | PO: Plate orientation | COA: Certificate of analysis | SDS: Material Safety Data Sheet
Sorbent Due to the nonspecific interaction with anti-CCDs present in normal human or animal sera, we strongly recommend using 12.5 µg of our sorbent SOR0001 on the analyzed sera in any immunoassay.
Formats
Liquid protein solution or dry powder (lyophilised) in vials of 0.1 mg, 1 mg and bulk
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For research and comercial use IVD only (*)

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