Babesiosis (or piroplasmosis)

The babesiosis is a disease caused by parasites of the genus Babesia, attacking red blood cells, invading erythrocytes and destroying them. It is a disease that mainly affects animals, although it can occur in humans. Babesiosis is transmitted through tick bites, although it can also happen through blood transfusion. The most common symptoms are malaise, fever, fatigue, chills, hemolytic anemia, and headaches, muscle or joint pain. In other cases, especially in immunocompromised or elderly patients, it can be life-threatening. However, this disease can also be asymptomatic, and persist for several months or years. The treatment consists of broad-spectrum antiprotozoals and antibiotics, and as prevention it is recommended to avoid endemic areas and use insect repellents. Since the symptoms are very similar to other diseases, the diagnosis is very important, and can be done through a peripheral blood smear under a microscope, a serological test or PCR.

Over 100 different Babesia species have been described, but fewer than 20 are of medical and veterinary importance. Babesia canis is a hemoprotozoan of the apicomplexa group that mainly affects dogs, and its severity is moderate to severe. Canine babesiosis has a worldwide distribution, although there is a greater impact in tropical and subtropical areas.

Animal infectious disease (mainly to dogs)

At Rekom Biotech, we desing and manufacture IVD reagents for diagnosis of Babesiosis (or piroplasmosis). Do not hesitate to contact us!

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BACT TO LIST OF INFECTIOUS DISEASES

Recombinant proteins

DISEASE/MICROORGANISM NAME REFERENCES DESCRIPTION DETAILS

Babesiosis (or piroplasmosis) / Babesia canis

Bc28.1
RAG0029 New
The major member of the Bc28 multigenic family
BcMSA1
RAG0020 Top product (Satisfaction guarantee)
RAG0020BIOT (biotinylated)
Merozoite Surface Antigen

Pipeline

Recombinant proteins

Design

Protein design from scratch, always trying to improve its antigenic capacity.

Verification

Search for the best DNA construction according to the design phase.

Expression system

Selection of the best expression system for the protein.

USP/DSP process tuning

Process adjustments to achieve an optimal seed, and the process to isolate our protein from the obtained seed.

Validation

Validation and full quality control.

BcSA1 for Babesiosis (or piroplasmosis) caused by Babesia canis (animal)
USP/DSP process tuning