Ara h 9 is a lipid transfer protein (LTP) and a major allergen in peanut-allergic patients from the Mediterranean region. Nonspecific lipid transfer proteins (LTPs) represent potent pollen and food allergens. Exist two Ara h 9 isoforms: Ara h 9.01 and Ara h 9.02. The two Ara h 9 isoforms displayed similar IgE reactivity. CD spectroscopy revealed similar secondary structures between Ara h 9 and Pru p 3. The Ara h 9 isoforms showed 62–68% amino acid sequence identity with Pru p 3. In peanut-allergic patients with concomitant peach allergy, Ara h 9 showed a weaker allergenic potency than Pru p 3 in histamine release assays. Therefore, Ara h 9 can induce histamine release from basophils, but to a lesser extent than Pru p 3.
For research and comercial use IVD only (*)
(*) Our IVD reagents are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. You can get more information about the general features and about the shipping, storage, defrost, manipulation and stability of all of our reagents. In addition, we follow a rigorous quality control for each lot.