Syphilis

Syphilis is a sexually transmitted disease (STD) caused by the bacteria Treponema pallidum. The transmission is through the sore of an infected person during sexual activity, by coming into contact with cuts or abrasions on the skin or mucous membranes. It can also be transmitted during pregnancy or childbirth (congenital syphilis), as well as through blood transfusions. Syphilis develops in stages, with symptoms varying with each: primary (sores at the original site of infection), secondary (skin rash, swollen lymph nodes, and fever), latent (without signs or symptoms) and tertiary (serious medical problems in the heart, brain and other organs, even causing death). At any stage, syphilis can spread and, among other things, cause damage to the brain, nervous system, and eye. Congenital syphilis can cause premature birth or even death before or after birth. In infected babies, in most cases there are no symptoms, except for a rash on the hands and feet on some occasions. Subsequently, deafness and dental and nasal deformities may appear. The most common treatment to treat this disease is penicillin, or any antibiotic in case of having an allergic reaction to it, and as a prevention strong> practicing safe sex and getting tested for STDs regularly is recommended. The diagnosis of syphilis is made through blood tests to detect antibodies against the disease, or analysis of the cerebrospinal fluid if there is involvement of the nervous system.

It is estimated that there are 7 million new syphilis infections in the world every year. In the early stages it can occur without producing any symptoms, but if left untreated, it can affect the entire body. Between 15-30% of people infected with syphilis who do not receive treatment will progress to the tertiary stage. Since 2000, the number of cases in the primary and secondary stages have increased among men.

Human infectious disease.

At Rekom Biotech, we desing and manufacture IVD reagents for diagnosis of Syphilis. Do not hesitate to contact us!

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BACT TO LIST OF INFECTIOUS DISEASES

Recombinant proteins

DISEASE/MICROORGANISM NAME REFERENCES DESCRIPTION DETAILS

Syphilis / Treponema pallidum

ChimSyphilis1
RAG0046 (chimera)
RAG0046BIOT (biotinylated)
Recombinant chimeric antigen for Treponema pallidum
ChimSyphilis2
RAG0064 (chimera)
RAG0064BIOT (biotinylated)
Recombinant chimeric antigen for Treponema pallidum
TmpA
RAG0073
Membrane lipoprotein
Tpp15
RAG0009
RAG0009BIOT (biotinylated)
Membrane lipoprotein
Tpp17
RAG0008
RAG0008BIOT (biotinylated)
Membrane lipoprotein
Tpp47
RAG0010
RAG0010BIOT (biotinylated)
Membrane lipoprotein