Chimeras

At Rekom Biotech, we have specialized in the design and production of next-generation proteins: chimeras or proteins composed of multiple epitopes, which have improved their antigenic properties, such as sensitivity and specificity. Furthermore, one main advantage of the multi-epitope chimeric proteins is avoiding the use of protein mixtures in your assay. The limited number of binding sites and the different affinities of proteins for these sites could result in reproducibility issues.

Take a look at our chimeric proteins and do not hesitate to contact us if you need anything.

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DISEASE/MICROORGANISM NAME REFERENCES DESCRIPTION DETAILS

Chagas / Trypanosoma cruzi

ChimChagas1
RAG0093 (chimera) Top product (Satisfaction guarantee)
Recombinant chimeric antigen for Chagas detection
ChimChagas2
RAG0094 (chimera) Top product (Satisfaction guarantee)
Recombinant chimeric antigen for Chagas detection
ChimChagas3
RAG0096 (chimera) Top product (Satisfaction guarantee)
Recombinant chimeric antigen for Chagas detection

Cytomegalovirus infection (CMV)

ChimCMV1
RAG0109 (chimera) Top product (Satisfaction guarantee)
Recombinant chimeric antigen which contains several antigenic determinants for CMV
ChimCMV2
RAG0110 (chimera)
Recombinant chimeric antigen for CMV detection

Dirofilariasis / Dirofilaria immitis

ChimDiT33
RAG0014 (chimera) New
Recombinant quimeric antigen for Dirofilaria immitis

Lyme borreliosis (or Lyme disease)

ChimLyme
RAG0027 (B. burgdorferi, chimera)
Recombinant chimeric antigen for Borrelia burgdorferi

Syphilis / Treponema pallidum

ChimSyphilis1
RAG0046 (chimera)
Recombinant chimeric antigen for Treponema pallidum
ChimSyphilis2
RAG0064 (chimera)
Recombinant chimeric antigen for Treponema pallidum

Toxoplasmosis / Toxoplasma gondii

ChimToxo1
RAG0058 (chimera)
Recombinant chimeric antigen ChimToxo1 for toxoplasmosis detection (SAG1 and GRA8)

Tuberculosis (TB) / Mycobacterium tuberculosis (Koch's bacillus)

CFP10:ESAT6
RAG0060 (chimera)
Recombinant chimeric antigen formed by the proteins CFP10 and ESAT6
Chimera
Figure 1. Chimeras or proteins composed of multiple epitopes
EPITOPE ANALYSIS

Epitope analysis

SEQUENCE ANALYSIS

Sequence analysis

3D STUDIES

3D studies