Lyme borreliosis (or Lyme disease)

Lyme disease is a multisystemic infectious disease caused by bacteria of the genus Borrelia, being the most relevant Borrelia burgdorferi, Borrelia afzelii and Borrelia garinii. Borreliosis is transmitted through tick bites, although it can also be transmitted by infected mosquitoes, fleas, or other insects. It affects humans and animals, mainly dogs, horses, and occasionally cattle. The main reservoirs for this spirochete are the white-footed mouse and the white-tailed deer. The most common symptoms are skin rash, fever, headache, and fatigue. If the disease is not treated or recognized early, more severe symptoms can develop and spread to the joints, heart, and nervous system. The treatment consists of antibiotics, which completely cure the disease if treated in time, and as a prevention it is recommended to avoid endemic areas and use insect repellents. The diagnosis of Lyme disease is complicated, since it has symptoms common to other diseases. Diagnostic tests usually help detect the disease, being the most common those that detect specific antibodies against the bacteria.

Lyme disease was discovered in the 1970s, and until two decades ago it only affected the northernmost part of the United States. Climate change and globalization have caused it to spread throughout the world: half a million people are diagnosed annually. The most prone areas are the United States, Europe and Asia. It is one of the world's most common tick-borne diseases for dogs, but only causes symptoms in 5-10% of infected dogs.

Human and animal infectious disease (mainly to dogs, horses and occasionally in beef cattle)

At Rekom Biotech, we desing and manufacture IVD reagents for diagnosis of Lyme borreliosis (or Lyme disease). Do not hesitate to contact us!

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BACT TO LIST OF INFECTIOUS DISEASES

Recombinant proteins

DISEASE/MICROORGANISM NAME REFERENCES DESCRIPTION DETAILS

Lyme borreliosis (or Lyme disease)

ChimLyme
RAG0027 (B. burgdorferi, chimera)
Recombinant chimeric antigen for Borrelia burgdorferi
flagellin B
RAG0054 (B. afzelii) New
RAG0055 (B. burgdorferi) New
RAG0072 (B. garinii) New
Internal central portion of 41 kDa flagelline B protein
ospC
RAG0034 (B. garinii)
RAG0042 (B. afzelii)
RAG0043 (B. burgdorferi)
Outer membrane antigen
VlsE
RAG0022 (B. garinii)
RAG0102 (B. afzelii)
Major variable Surface antigen