Outer membrane protein ospC is essential for the invasive strategy of the pathogenic spirochete responsible for Lyme disease. Detection of anti-OspC borreliacidal antibodies, especially IgM antibodies, in early Lyme borreliosis sera provides additional evidence that borreliacidal antibody detection may be useful for the serodiagnosis of early Lyme borreliosis.
REFERENCES
RAG0034 (B. garinii) WB, DB, Indirect ELISA, positive control in direct ELISA RAG0042 (B. afzelii) WB, DB, Indirect ELISA, positive control in direct ELISA RAG0043 (B. burgdorferi) WB, DB, Indirect ELISA, positive control in direct ELISA
GENE
ospC
DESCRIPTION
Outer membrane antigen
PURITY
>95% in a SDS-PAGE
SHIPPING AND STORAGE CONDITIONS
Proteins will be shipped on dry ice or ice pack. Upon arrival they should be stored at -20ºC to -80ºC. Avoid multiple freeze/thaw cycles
STABILITY
The protein will remain stable for four years if stored frozen
SPECIFICITY
The protein is immunoreactive against seropositive individuals to Borreliosis or Lyme disease
