Recombinant antigens
CagA(Dom III)
for Helicobacter pylori
CagA antigen (Cytotoxin-associated gene A) is a protein produced by the bacteria Helicobacter pylori (H. pylori), a pathogen known to cause various gastric diseases, such as gastritis, peptic ulcers and gastric cancer. Not all strains of H. pylori have the cagA gene. Strains that have it are usually associated with greater severity of the disease, being associated with a greater risk of developing more serious conditions, such as peptic ulcers or gastric cancer.
Domain III of this protein, together with Domain II, constitutes part of the so-called 'intermediate' region. It is known that the middle domain harbors a binding site for integrin α5β1, the receptor required for the delivery of CagA into gastric epithelial cells. Furthermore, it contains positively charged regions that are important for membrane binding.
- NAME
- Caga(dom iii)
- DESCRIPTION
- Cytotoxin-associated gene A(Dom III)
- GEN
- cagA
- PURITY
- >95% by observation on SDS-PAGE electrophoresis
- Formats
Liquid solution or dry powder (lyophilised) in vials of 0.1 mg*, 1 mg and bulk.
*under availability, for liquid format
* Our IVD reagents are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. In addition, we follow a rigorous quality control for each lot.
References of Recombinant antigen CagA
Folletos
Videos
Reagent sheet
- NAME
- CagA(Dom III)
- DESCRIPTION
- Cytotoxin-associated gene A(Dom III)
- PURITY
- >95% by observation on SDS-PAGE electrophoresis
- Formats
Liquid solution or dry powder (lyophilised) in vials of 0.1 mg*, 1 mg and bulk.
*under availability, for liquid format
* Our IVD reagents are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. In addition, we follow a rigorous quality control for each lot.
