Flagellin is the subunit protein that polymerizes to form the filaments of bacterial flagella. It consists of 336 amino acids. Borrelia flagellin contains conserved and semi-conserved regions located at the N- and C-termini of the protein, whereas the central area exhibits variability. Many Borrelia-specific epitopes were found in this variable central region, and therefore, it has been described as a suitable antigen to test bacterial genera.
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