Protein G

Protein G is a bacterial cell wall protein expressed on the surface of certain strains of Group G and C Streptococcus. It presents two main domains: independent binding sites for the Fab and Fc fragments of human immunoglobulin G (IgG), as well as regions that allow binding to albumin and the bacterial cell surface. Its binding to the Fc region occurs via a non-immune mechanism and shows high affinity for almost all mammalian IgG classes, including all human subclasses (IgG1, IgG2, IgG3, and IgG4), as well as rabbit, mouse, and goat IgG. Likewise, protein G binds effectively to various subclasses of mouse and rat monoclonal antibodies, presenting a broader binding spectrum than protein A in rodents. Especially for mouse mAb IgG1, protein G is usually preferred over protein A.

References of Protein G

Folletos

• Rekom Biotech Catalog
• Recombinant proteins for in vitro diagnosis of human infectious diseases
• Recombinant proteins for in vitro diagnosis of animal infectious diseases
• Gemini ha dicho Recombinant proteins for vector-borne diseases

Videos

• How to reconstitute lyophilized vials