gG2 contains the immunogenic regions of the glycoprotein G from the Herpes simplex virus type 2. The envelope glycoprotein G (gG) proteins are the only HSV antigens known to induce type-specific antibody responses and are therefore used in serological assays to discriminate between HSV-1 and HSV-2 infection. Although exist a strong serological cross-reactivity between HSV-1 and HSV-2, the use of the recombinant HSV-2 glycoprotein G (gG2) allows determining only HSV-2 type specific IgG antibodies. Prompt recognition of herpes simplex infection and early initiation of therapy are of utmost importance in the managing of the disease.
FOR RESEARCH USE ONLY