Hepatitis B virus core protein (HBcAg) is a crucial serology marker of hepatitis B infection and patient follow-up. It is a 21-kDa protein with the intrinsic capacity to self-assemble as a capsid-like particle. It is a nuclear protein that self-assembles during viral replication in liver cells to form a regular 20-hedron structure. It is observed with great frequency in immunosuppressed patients with chronic hepatitis. A good An anti-HBc is important in the identification of HBV-infected individuals who are negative for hepatitis B surface antigen (HBsAg), but are positive for anti-HBc, in an effort to prevent the contamination of blood transfusion products with HBV.
For research and comercial use IVD only (*)
(*) Our IVD reagents are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. You can get more information about the general features and about the shipping, storage, defrost, manipulation and stability of all of our reagents. In addition, we follow a rigorous quality control for each lot.