Recombinant antigen NcGRA7 for Neospora caninum

Neospora caninum

GRA7 is an excretory Neospora caninum dense granule antigen and a highly immunogenic protein of the parasite. Although GRA proteins appear to be related to intracellular parasite development, previous studies revealed that NcGRA7 might be involved in the initial host cell invasion process of N. caninum. Some published studies showed high specificity and intense signal conferred by monoclonal Ab produced against NcGRA7, which render them as strong candidates for use in developing a competitive ELISA for diagnosis of N. caninum infection. This technique would be especially useful in dogs, for which current serological techniques lack the sensitivity and specificity of those used in bovines (Silva et al. 2007, Ghalmi et al. 2009).

Recombinant antigen for the diagnosis of Neosporosis caused by Neospora caninum, an animal infectious disease (mainly warm-blooded mammals, mainly dogs and cattle).

Dense granule antigen GRA7
> 95% by observation on SDS-PAGE electrophoresis
Cat number
SKU Source Applications In-house validation Details
RAG0024 E. coli WB, DB, IE, DE, CLIA, LF - Example of a certificate of analysis Material Safety Data Sheet
RAG0024BIOT (biotinylated) E. coli WB, DB, CE, NP, PO - Example of a certificate of analysis Material Safety Data Sheet
WB: Western Blot | DB: Dot Blot | IE: Indirect ELISA | DE: positive control in Direct ELISA | CLIA: Chemiluminescent immunoassay | LF: Lateral-Flow | CE: Capture ELISA | DAS: Double Antigen Sandwich ELISA | NP: Nanoparticles binding | PO: Plate orientation | COA: Certificate of analysis | SDS: Material Safety Data Sheet
This protein is available monobiotinylated
Liquid solution or dry powder (lyophilised) in vials of 0.1 mg*, 1 mg and bulk
* under availability, for liquid format

For research and comercial use IVD only (*)

(*) Our IVD reagents are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. You can get more information about the general features and about the shipping, storage, defrost, manipulation and stability of all of our reagents. In addition, we follow a rigorous quality control for each lot.

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