pp52 (UL44) is the DNA polymerase processivity subunit of CMV. It is a phosphorylated protein, with a high presence in the virus and DNA binding capacity. pp52 corresponds to an immediate early antigen. It is one of the serological targets for detection of CMV-specific IgM.
REFERENCES
RAG0090 WB, DB, Indirect ELISA, positive control in direct ELISA, CLIA
GENE
UL44
DESCRIPTION
DNA polymerase processivity subunit
PURITY
>95% in a SDS-PAGE
SHIPPING AND STORAGE CONDITIONS
Proteins will be shipped on dry ice or ice pack. Upon arrival they should be stored at -20ºC to -80ºC. Avoid multiple freeze/thaw cycles
STABILITY
The protein will remain stable for four years if stored frozen
SPECIFICITY
The protein is immunoreactive against seropositive individuals to Cytomegalovirus infection
IVD
Serodiagnosis of latent infection or active infection in immunocompetent individuals; presence of CMV in associated diseases and transplantation, especially in immunocompromised individuals; diagnosis of congenital infection in newborns and intrauterine primary infection in pregnant women
